Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 19/20 | 1.00 |
| ▸ | HTR1D | P28221 | 11/20 | 0.56 |
| ▸ | HTR1E | P28566 | 2/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | DRD5 | P21918 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 12/20 | 0.52 |
| ▸ | HTR1B | P28222 | 11/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909202 | 0.87 | HTR1F (1.00) | HTR1FHTR1DHTR1EHTR1AHTR1B | |
| SCHEMBL30909192 | 0.86 | HTR1F (1.00) | HTR1FHTR1DHTR1ECHRM5DRD5 | |
| SCHEMBL30909022 | 0.84 | HTR1F (1.00) | HTR1FHTR1DHTR1EHTR1AHTR1B | |
| SCHEMBL12021094 | 0.73 | HTR1F (0.72) | HTR1FHTR1DHTR1ECHRM5DRD5 | |
| SCHEMBL4503014 | 0.73 | HTR1F (0.68) | HTR1FHTR1DHTR1ECHRM5DRD5 | |
| SCHEMBL7011605 | 0.72 | HTR1F (0.81) | HTR1FHTR1DHTR1EHTR1AHTR1B | |
| Lasmiditan SCHEMBL536057 | 0.72 | HTR1F (1.00) | HTR1FHTR1DHTR1ECHRM5DRD5 | |
| Lasmiditan SCHEMBL29376817 | 0.72 | HTR1F (1.00) | HTR1FHTR1DHTR1ECHRM5DRD5 | |
| Hydrochloric Acid SCHEMBL1198211 | 0.72 | HTR1F (0.70) | HTR1FHTR1DHTR1ECHRM5DRD5 | |
| Hydrochloric Acid SCHEMBL4493509 | 0.72 | HTR1F (0.67) | HTR1FHTR1DHTR1ECHRM5DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125645-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ LP (CA) | 2026-05-07 | — | — | US | disclosed |
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125645-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | HTR1F, HTR1A, HTR1D | HTR1F 1/4885HTR1D 3/4885HTR1E 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.