Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 5/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | HTR1D | P28221 | 15/20 | 0.49 |
| ▸ | HTR1B | P28222 | 12/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382624 | 1.00 | HTR1F (0.50) | HTR1FHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL30908902 | 0.91 | HTR2A (0.44) | HTR1FHTR1ADRD2CHRM2HRH3 | |
| SCHEMBL8385565 | 0.91 | HTR2A (0.44) | HTR1FHTR1ADRD2CHRM2HRH3 | |
| SCHEMBL8382161 | 0.89 | HTR1F (0.39) | HTR1FHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL30908964 | 0.89 | HTR1F (0.39) | HTR1FHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL8382151 | 0.87 | RAB9A (0.41) | HTR1FHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL8383089 | 0.86 | MAPT (0.43) | HTR1FHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL30908923 | 0.86 | MAPT (0.43) | HTR1FHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL8387630 | 0.86 | KCNK3 (0.37) | HTR1FHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL8381834 | 0.85 | RAB9A (0.40) | HTR1FHTR1AHTR1DHTR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |