Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 17/20 | 0.72 |
| ▸ | HTR1D | P28221 | 2/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.67 |
| ▸ | DRD5 | P21918 | 1/20 | 0.67 |
| ▸ | HTR1E | P28566 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531510 | 1.00 | HTR1F (0.72) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL30909102 | 0.85 | HTR1F (0.78) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2531513 | 0.85 | HTR1F (0.78) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2535880 | 0.85 | HTR1F (0.78) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL30909139 | 0.85 | HTR1F (0.78) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2533719 | 0.84 | HTR1F (1.00) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| Hydrochloric Acid SCHEMBL2531437 | 0.83 | HTR1F (0.98) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL2540244 | 0.82 | HTR1F (0.81) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| Hydrochloric Acid SCHEMBL2535877 | 0.82 | HTR1F (0.79) | HTR1FHTR1DCHRM5DRD5HTR1E | |
| SCHEMBL30730002 | 0.81 | HTR1F (0.85) | HTR1FHTR1DCHRM5DRD5HTR1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |