SCHEMBL30909351

SCHEMBL30909351

Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 9/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
ALDH1A1 P00352 6/20 0.55
CYP1A2 P05177 3/20 0.55
HPGD P15428 3/20 0.55
LMNA P02545 3/20 0.55
NPSR1 Q6W5P4 2/20 0.55
CYP3A4 P08684 2/20 0.55
MAPT P10636 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
TP53 P04637 1/20 0.55
ALOX15 P16050 1/20 0.55
NFKB1 P19838 1/20 0.55
HIF1A Q16665 1/20 0.55
GMNN O75496 1/20 0.55
APEX1 P27695 1/20 0.55
PMP22 Q01453 1/20 0.55
CYP2C19 P33261 2/20 0.54
CYP2C9 P11712 1/20 0.54
RAB9A P51151 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6238201 1.00 HTT (0.61) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL6087572 0.94 HTT (0.61) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL10942912 0.87 HTT (0.54) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL18612170 0.85 HTT (0.66) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL10677656 0.85 HTT (0.61) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL8508099 0.85 HTT (0.66) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL17859587 0.85 HTT (0.66) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL10944282 0.85 CYP1A2 (0.64) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL17302643 0.83 ALDH1A1 (0.57) HTTL3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL29652002 0.83 ALDH1A1 (0.57) HTTL3MBTL1ALDH1A1CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700400-A Preparation method of quizalofop-p-ethyl 江苏丰山生化科技有限公司 2024-03-15 CN disclosed