Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 9/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909351 | 0.94 | HTT (0.61) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL6238201 | 0.94 | HTT (0.61) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL8508099 | 0.82 | HTT (0.66) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL10954923 | 0.82 | HTT (0.61) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL10942912 | 0.82 | HTT (0.54) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL27259682 | 0.81 | ALDH1A1 (0.60) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL30534581 | 0.80 | HTT (0.74) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL10904809 | 0.80 | HTT (0.74) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL18612170 | 0.79 | HTT (0.66) | HTTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL17859587 | 0.79 | HTT (0.66) | HTTL3MBTL1ALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539699-A1 | 4- 7'-HALO-2-QUINO (XA-) LINYLOXY!PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS | WAYNE STATE UNIVERSITY (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004005260-A1 | A-`7-HALO-2-QUINO (XA-) LINYLOXY!PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS | WAYNE STATE UNIVERSITY (US) | 2004-01-15 | — | — | WO | claimed |
| US-7109341-B2 | Therapeutic amides | WAYNE STATE UNIVERSITY (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1539699-A1 | 4- 7'-HALO-2-QUINO (XA-) LINYLOXY!PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS | WAYNE STATE UNIVERSITY (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040132618-A1 | Therapeutic amides | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2004-07-08 | — | — | US | disclosed |
| WO-2004005260-A1 | A-`7-HALO-2-QUINO (XA-) LINYLOXY!PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS | WAYNE STATE UNIVERSITY (US) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132618-A1 | Therapeutic amides | HDAC5, HDAC6, ASAH2 | HTT 2419/4885L3MBTL1 2062/4885ALDH1A1 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.