Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | JAK1 | P23458 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | PAICS | P22234 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PHKG1 | Q16816 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911847 | 0.90 | FLT3 (0.34) | SLC6A4FLT3JAK2JAK1JAK3 | |
| SCHEMBL19986192 | 0.81 | L3MBTL1 (0.38) | TLR7POLBALDH1A1 | |
| SCHEMBL25359893 | 0.78 | L3MBTL1 (0.47) | IRAK4DRD2DRD1DRD4DRD5 | |
| SCHEMBL19438892 | 0.77 | PDK2 (0.33) | — | |
| SCHEMBL12332962 | 0.76 | JAK2 (0.38) | FLT3JAK2JAK1JAK3TYK2 | |
| SCHEMBL20713609 | 0.75 | GBA1 (0.35) | — | |
| SCHEMBL671403 | 0.75 | MAPT (0.39) | FLT3JAK2JAK1JAK3TYK2 | |
| SCHEMBL30911491 | 0.74 | MAPT (0.33) | MAPT | |
| SCHEMBL27407689 | 0.74 | KIT (0.36) | IRAK4 | |
| SCHEMBL10264507 | 0.73 | TLR7 (0.41) | FLT3JAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980297-A | Substituted aminopyridine compounds as EGFR inhibitors | 柳韩洋行 | 2024-05-03 | — | — | CN | disclosed |