Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.35 |
| ▸ | MTOR | P42345 | 4/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911502 | 0.82 | ALDH1A1 (0.33) | ATRGPR6ACACBPIK3CAALDH1A1 | |
| SCHEMBL30911486 | 0.81 | IRAK4 (0.39) | ATRATRIPGPR6PIK3CAALDH1A1 | |
| SCHEMBL30911592 | 0.78 | ATR (0.40) | ATRATRIPGPR6PIK3CAMTOR | |
| SCHEMBL30911690 | 0.78 | IRAK4 (0.43) | ATRGPR6ACACBPIK3CAMTOR | |
| SCHEMBL30911635 | 0.77 | KDM4E (0.45) | ATR | |
| SCHEMBL31262589 | 0.77 | KDM4E (0.39) | GPR6PIK3CAMTORMAP4K4ALDH1A1 | |
| SCHEMBL30911509 | 0.77 | IRAK4 (0.41) | PIK3CAMTOR | |
| SCHEMBL30911789 | 0.77 | INSR (0.43) | ATREGFR | |
| SCHEMBL30911597 | 0.75 | IRAK4 (0.41) | ATRACACBAOC3 | |
| SCHEMBL30911787 | 0.75 | TYMP (0.40) | GPR6PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980297-A | Substituted aminopyridine compounds as EGFR inhibitors | 柳韩洋行 | 2024-05-03 | — | — | CN | disclosed |