Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912529 | 1.00 | MAPT (0.45) | MAPTALDH1A1MEN1THRBKMT2A | |
| SCHEMBL13657915 | 1.00 | MAPT (0.45) | MAPTALDH1A1MEN1THRBKMT2A | |
| SCHEMBL3413859 | 1.00 | MAPT (0.45) | MAPTALDH1A1MEN1THRBKMT2A | |
| SCHEMBL14642921 | 0.89 | MAPT (0.44) | MAPTALDH1A1MEN1THRBKMT2A | |
| SCHEMBL30912555 | 0.83 | MAPT (0.49) | MAPTALDH1A1GAAKDM4ECHRNA7 | |
| SCHEMBL30912595 | 0.83 | MAPT (0.49) | MAPTALDH1A1GAAKDM4ECHRNA7 | |
| SCHEMBL25900470 | 0.81 | CHRNA7 (0.40) | CHRNA7KCNH2 | |
| SCHEMBL25894589 | 0.81 | MAPT (0.40) | MAPTALDH1A1MEN1THRBKMT2A | |
| SCHEMBL3415212 | 0.77 | CHRNA7 (0.36) | CHRNA7KCNH2 | |
| SCHEMBL21641736 | 0.77 | KCNH2 (0.44) | MAPTALDH1A1KMT2AGAAPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619406-A1 | TRICYCLIC COMPOUNDS | Schrödinger, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107393-A1 | TRICYCLIC COMPOUNDS | SCHRÖDINGER, INC. (US) | 2024-05-23 | — | — | WO | disclosed |