Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890066 | 0.87 | MAPT (0.36) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13657915 | 0.81 | MAPT (0.45) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL30912434 | 0.81 | MAPT (0.45) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL30912529 | 0.81 | MAPT (0.45) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL3413859 | 0.81 | MAPT (0.45) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL14642921 | 0.74 | MAPT (0.44) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL328198 | 0.72 | ALDH1A1 (0.56) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL3413033 | 0.70 | ALDH1A1 (0.49) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL10035939 | 0.69 | MAPT (0.56) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL25889890 | 0.69 | HTR2A (0.36) | GAAALOX15SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |