Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912465 | 1.00 | IRAK4 (0.41) | IRAK4AAK1MMP13PAX8HTR7 | |
| SCHEMBL30912458 | 1.00 | IRAK4 (0.41) | IRAK4AAK1MMP13PAX8HTR7 | |
| SCHEMBL1830610 | 0.83 | KDM4E (0.41) | IRAK4AAK1MMP13PAX8LMNA | |
| SCHEMBL24468312 | 0.80 | LMNA (0.40) | AAK1MMP13PAX8SSTR4SOS1 | |
| SCHEMBL29686000 | 0.80 | LMNA (0.40) | AAK1MMP13PAX8SSTR4SOS1 | |
| SCHEMBL27280938 | 0.77 | IRAK4 (0.41) | IRAK4AAK1LMNAKMT2A | |
| SCHEMBL16837680 | 0.77 | AAK1 (0.43) | AAK1SOS1LMNABACE1 | |
| SCHEMBL68085 | 0.76 | PAX8 (0.42) | IRAK4PAX8HTR7CLK1SSTR4 | |
| SCHEMBL10261793 | 0.75 | USP30 (0.39) | IRAK4AAK1MMP13PAX8CLK1 | |
| SCHEMBL19236694 | 0.74 | AAK1 (0.39) | AAK1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619406-A1 | TRICYCLIC COMPOUNDS | Schrödinger, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107393-A1 | TRICYCLIC COMPOUNDS | SCHRÖDINGER, INC. (US) | 2024-05-23 | — | — | WO | disclosed |