Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912534 | 1.00 | POLB (0.46) | POLBMAPTMEN1KMT2ASIRT6 | |
| SCHEMBL30912409 | 1.00 | POLB (0.46) | POLBMAPTMEN1KMT2ASIRT6 | |
| SCHEMBL2537629 | 0.91 | POLB (0.49) | POLBMAPTMEN1KMT2ASIRT6 | |
| Fluoride SCHEMBL2534999 | 0.89 | POLB (0.47) | POLBMAPTMEN1KMT2ASIRT6 | |
| SCHEMBL3246831 | 0.77 | CA2 (0.52) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1782288 | 0.77 | MAPT (0.38) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3240619 | 0.76 | MAPT (0.60) | POLBMAPTMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL3264480 | 0.76 | CA2 (0.51) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22805646 | 0.76 | CHRNA7 (0.44) | — | |
| SCHEMBL30912556 | 0.76 | ALDH1A1 (0.39) | POLBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619406-A1 | TRICYCLIC COMPOUNDS | Schrödinger, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107393-A1 | TRICYCLIC COMPOUNDS | SCHRÖDINGER, INC. (US) | 2024-05-23 | — | — | WO | disclosed |