Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912594 | 1.00 | USP2 (0.40) | USP2SMN1; SMN2EPHA2USP30SMARCA2 | |
| SCHEMBL30912582 | 1.00 | USP2 (0.40) | USP2SMN1; SMN2EPHA2USP30SMARCA2 | |
| SCHEMBL30374041 | 0.88 | GRM5 (0.45) | USP2SMN1; SMN2USP30SMARCA2SMARCA4 | |
| SCHEMBL25184732 | 0.87 | TRPV3 (0.42) | USP2SMN1; SMN2USP30TRPV3GPR119 | |
| SCHEMBL25184731 | 0.85 | IDH1 (0.47) | USP2SMN1; SMN2USP30GPR119 | |
| SCHEMBL30912414 | 0.83 | TRPV3 (0.52) | USP30TRPV3PARP1GPR119 | |
| SCHEMBL30912532 | 0.83 | TRPV3 (0.52) | USP30TRPV3PARP1GPR119 | |
| SCHEMBL31383577 | 0.83 | TRPV3 (0.52) | USP30TRPV3PARP1GPR119 | |
| SCHEMBL30373617 | 0.82 | GPR119 (0.50) | USP2SMN1; SMN2USP30GPR119 | |
| SCHEMBL14240648 | 0.80 | TRPV3 (0.51) | TRPV3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619406-A1 | TRICYCLIC COMPOUNDS | Schrödinger, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107393-A1 | TRICYCLIC COMPOUNDS | SCHRÖDINGER, INC. (US) | 2024-05-23 | — | — | WO | disclosed |