Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921576 | 0.81 | MEN1 (0.35) | KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL4802333 | 0.76 | NPC1 (0.51) | KMT2ANPC1RAB9AALDH1A1TSHR | |
| SCHEMBL4332580 | 0.76 | NPC1 (0.51) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL17467189 | 0.74 | KMT2A (0.49) | KMT2AMEN1HTTL3MBTL1NPC1 | |
| SCHEMBL6577360 | 0.72 | MEN1 (0.33) | KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL30440629 | 0.72 | ALDH1A1 (0.41) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL531523 | 0.72 | RIPK1 (0.48) | KMT2AMEN1HTTL3MBTL1NPC1 | |
| SCHEMBL8773482 | 0.72 | MEN1 (0.69) | KMT2AMEN1HTTL3MBTL1NPC1 | |
| SCHEMBL17258048 | 0.71 | KMT2A (0.51) | KMT2AMEN1HTTL3MBTL1NPC1 | |
| SCHEMBL17257984 | 0.70 | MEN1 (0.43) | KMT2AMEN1HTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344372-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118255773-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118255774-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-06-28 | — | — | CN | disclosed |