SCHEMBL30912928

SCHEMBL30912928

O=C(Nc1cccc(Br)c1)c1c[nH]c2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.67
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
CFTR P13569 5/20 0.60
SCN4A P35499 1/20 0.59
SCN9A Q15858 1/20 0.59
SCN3A Q9NY46 1/20 0.59
GOT1 P17174 1/20 0.59
P2RX1 P51575 1/20 0.58
NPC1 O15118 2/20 0.58
EGFR P00533 1/20 0.56
ALDH1A1 P00352 1/20 0.54
HTT P42858 1/20 0.54
MAOB P27338 2/20 0.54
RAB9A P51151 1/20 0.53
NHERF1 O14745 1/20 0.52
GABRA1 P14867 1/20 0.52
GABRB1 P18505 1/20 0.52
GABRA5 P31644 1/20 0.52
GABRA3 P34903 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176358 1.00 STING1 (0.67) STING1MEN1KMT2ACFTRSCN4A
SCHEMBL29176620 0.89 NHERF1 (0.58) STING1MEN1KMT2ACFTRSCN4A
SCHEMBL29176616 0.89 CFTR (0.58) STING1MEN1KMT2ACFTRSCN4A
SCHEMBL30912930 0.85 P2RX1 (0.50) STING1MEN1KMT2ACFTRSCN4A
SCHEMBL29176341 0.85 P2RX1 (0.50) STING1MEN1KMT2ACFTRSCN4A
SCHEMBL20567704 0.85 STING1 (0.64) STING1MEN1KMT2ACFTRGOT1
SCHEMBL4430677 0.84 CFTR (0.80) MEN1KMT2ACFTRNPC1ALDH1A1
SCHEMBL30695128 0.84 NHERF1 (0.65) MEN1KMT2ACFTRSCN4ASCN9A
SCHEMBL29176615 0.84 NHERF1 (0.65) MEN1KMT2ACFTRSCN4ASCN9A
SCHEMBL29176625 0.84 MEN1 (0.62) MEN1KMT2ACFTRSCN4ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024109642-A1 USE OF BENZOAZACYCLIC COMPOUND AS ALLOSTERIC MODULATOR OF β2-ADRENOCEPTOR 常州大学 2024-05-30 WO disclosed