Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | F2R | P25116 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.46 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912930 | 1.00 | P2RX1 (0.50) | P2RX1STING1ALDH1A1HTTMEN1 | |
| SCHEMBL29176352 | 0.86 | CFTR (0.57) | HTTMEN1KMT2ANPC1LMNA | |
| SCHEMBL30912928 | 0.85 | STING1 (0.67) | P2RX1STING1ALDH1A1HTTMEN1 | |
| SCHEMBL29176358 | 0.85 | STING1 (0.67) | P2RX1STING1ALDH1A1HTTMEN1 | |
| SCHEMBL28571455 | 0.84 | NHERF1 (0.65) | HTTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL30089269 | 0.84 | NHERF1 (0.65) | HTTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29176620 | 0.82 | NHERF1 (0.58) | P2RX1STING1ALDH1A1HTTMEN1 | |
| SCHEMBL10260257 | 0.81 | CFTR (0.57) | P2RX1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL29176343 | 0.81 | SORT1 (0.60) | ALDH1A1MEN1KMT2ANPC1NHERF1 | |
| SCHEMBL30762255 | 0.81 | SORT1 (0.60) | ALDH1A1MEN1KMT2ANPC1NHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447381-A | Indole amide derivative and its application in preparing beta 2 Use of adrenoreceptor allosteric antagonist medicaments | 常州大学 | 2024-01-26 | — | — | CN | disclosed |