Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740756 | 0.87 | KMT2A (0.47) | MAOBPRCPCYP19A1KMT2AMAPT | |
| SCHEMBL23088767 | 0.87 | KMT2A (0.47) | MAOBPRCPCYP19A1KMT2AMAPT | |
| SCHEMBL23088790 | 0.84 | POLB (0.42) | PRCPKMT2AMAPTMEN1LMNA | |
| SCHEMBL23088757 | 0.84 | MAOB (0.42) | MAOBPRCPCYP19A1KMT2AMAPT | |
| SCHEMBL30913033 | 0.84 | MAOB (0.42) | MAOBPRCPCYP19A1KMT2AMAPT | |
| SCHEMBL23088758 | 0.84 | KMT2A (0.40) | MAOBKMT2AMAPTMEN1LMNA | |
| SCHEMBL23088796 | 0.84 | L3MBTL1 (0.39) | — | |
| SCHEMBL23088750 | 0.79 | SLC6A2 (0.39) | KMT2AMEN1 | |
| SCHEMBL23118931 | 0.76 | CYP19A1 (0.42) | CYP19A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL23088782 | 0.75 | CYP19A1 (0.43) | MAOBCYP19A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084822-A | Preparation method for synthesizing chiral sulfonamide through nickel catalytic asymmetric reduction and chiral sulfonamide compound | 中国科学院大连化学物理研究所 | 2024-05-28 | — | — | CN | disclosed |