SCHEMBL30913033

SCHEMBL30913033

Cc1ccc(C2NS(=O)(=O)Oc3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.42
PRCP P42785 1/20 0.42
CYP19A1 P11511 1/20 0.39
KMT2A Q03164 4/20 0.36
MEN1 O00255 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 1/20 0.36
FFAR4 Q5NUL3 1/20 0.35
GID4 Q8IVV7 1/20 0.35
ALDH1A1 P00352 2/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23088757 1.00 MAOB (0.42) MAOBPRCPCYP19A1KMT2AMEN1
SCHEMBL29740756 0.87 KMT2A (0.47) MAOBPRCPCYP19A1KMT2AMEN1
SCHEMBL23088767 0.87 KMT2A (0.47) MAOBPRCPCYP19A1KMT2AMEN1
SCHEMBL23088790 0.84 POLB (0.42) PRCPKMT2AMEN1LMNAMAPT
SCHEMBL30913028 0.84 MAOB (0.42) MAOBPRCPCYP19A1KMT2AMEN1
SCHEMBL23088758 0.84 KMT2A (0.40) MAOBKMT2AMEN1LMNAMAPT
SCHEMBL30913024 0.84 CYP19A1 (0.43) MAOBCYP19A1KMT2AMEN1LMNA
SCHEMBL23088782 0.84 CYP19A1 (0.43) MAOBCYP19A1KMT2AMEN1LMNA
SCHEMBL23088772 0.82 GAA (0.48) MAOBCYP19A1KMT2AMEN1ALDH1A1
SCHEMBL30913023 0.81 ALDH1A1 (0.49) KMT2AALDH1A1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084822-A Preparation method for synthesizing chiral sulfonamide through nickel catalytic asymmetric reduction and chiral sulfonamide compound 中国科学院大连化学物理研究所 2024-05-28 CN disclosed