Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25170617 | 1.00 | BTK (0.40) | BTKGRM5RPS6KA2NTRK1AR | |
| SCHEMBL25170630 | 0.85 | BTK (0.37) | BTKGRM5 | |
| SCHEMBL30913575 | 0.85 | BTK (0.37) | BTKGRM5 | |
| SCHEMBL25173924 | 0.72 | BTK (0.52) | BTK | |
| SCHEMBL25170785 | 0.70 | LIPE (0.38) | KDM1ABUB1 | |
| SCHEMBL16794185 | 0.70 | BTK (0.44) | BTK | |
| SCHEMBL20054059 | 0.70 | BTK (0.40) | BTK | |
| SCHEMBL30434223 | 0.68 | BTK (0.49) | BTK | |
| SCHEMBL25169911 | 0.68 | BTK (0.49) | BTK | |
| SCHEMBL25983517 | 0.66 | ABL1 (0.47) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159532-A | Compound with BTK protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-06-07 | — | — | CN | disclosed |