Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561435 | 1.00 | MAPT (0.46) | MAPTKMT2ALMNAACSS2L3MBTL1 | |
| SCHEMBL13199189 | 0.89 | ACSS2 (0.51) | MAPTKMT2ALMNAACSS2TSHR | |
| SCHEMBL29879983 | 0.87 | MAPT (0.46) | MAPTKMT2ALMNAL3MBTL1ABCB11 | |
| SCHEMBL29136986 | 0.87 | MAPT (0.46) | MAPTKMT2ALMNAL3MBTL1ABCB11 | |
| SCHEMBL30628323 | 0.84 | ACSS2 (0.48) | MAPTKMT2ALMNAACSS2L3MBTL1 | |
| SCHEMBL31306494 | 0.84 | NPSR1 (0.50) | MAPTKMT2AACSS2L3MBTL1ALDH1A1 | |
| SCHEMBL2012390 | 0.84 | ACSS2 (0.48) | MAPTKMT2ALMNAACSS2L3MBTL1 | |
| SCHEMBL30032595 | 0.84 | TSHR (0.52) | MAPTKMT2ALMNATSHRALDH1A1 | |
| SCHEMBL17420520 | 0.83 | ACSS2 (0.47) | MAPTKMT2AACSS2TSHRALDH1A1 | |
| SCHEMBL17420423 | 0.83 | POLB (0.51) | MAPTLMNAACSS2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731634-A1 | SMALL-MOLECULE STABILIZERS OF THE CHREBP 14-3-3 INTERACTION | Technische Universiteit Eindhoven (NL) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025005795-A1 | SMALL-MOLECULE STABILIZERS OF THE CHREBP 14-3-3 INTERACTION | TECHNISCHE UNIVERSITEIT EINDHOVEN (NL) | 2025-01-02 | — | — | WO | disclosed |
| CN-118103351-A | Coronavirus inhibitors | 共晶制药公司 | 2024-05-28 | — | — | CN | disclosed |