Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29879983 | 1.00 | MAPT (0.46) | MAPTKMT2ALMNAABCB11CYP1A2 | |
| SCHEMBL1561435 | 0.87 | MAPT (0.46) | MAPTKMT2ALMNAABCB11CYP1A2 | |
| SCHEMBL30914092 | 0.87 | MAPT (0.46) | MAPTKMT2ALMNAABCB11CYP1A2 | |
| SCHEMBL27772056 | 0.84 | ABCB11 (0.47) | MAPTKMT2ALMNAABCB11CYP1A2 | |
| SCHEMBL31619458 | 0.83 | KCNN4 (0.43) | MAPTKMT2ACYP1A2CYP3A4CNR2 | |
| SCHEMBL30032595 | 0.83 | TSHR (0.52) | MAPTKMT2ALMNATSHRALDH1A1 | |
| SCHEMBL23005428 | 0.82 | ALDH1A1 (0.43) | MAPTKMT2ACYP1A2GAAALDH1A1 | |
| SCHEMBL10814021 | 0.82 | SCN5A (0.47) | MAPTKMT2ALMNAABCB11CYP1A2 | |
| SCHEMBL31619474 | 0.81 | TSHR (0.58) | MAPTKMT2ALMNAABCB11CYP1A2 | |
| SCHEMBL4526778 | 0.81 | PIN1 (0.51) | MAPTKMT2ALMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |