Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.75 |
| ▸ | HPGD | P15428 | 5/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | EP300 | Q09472 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | ATM | Q13315 | 6/20 | 0.57 |
| ▸ | GLA | P06280 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 5/20 | 0.51 |
| ▸ | CASP7 | P55210 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249851 | 1.00 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL13869309 | 0.90 | ALDH1A1 (0.86) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL8132354 | 0.86 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL5590828 | 0.85 | ALDH1A1 (0.78) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL29569907 | 0.85 | ALDH1A1 (0.77) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL28721602 | 0.85 | ALDH1A1 (0.77) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL14160786 | 0.84 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL28720726 | 0.84 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL808511 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL13869289 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271270-A | 3-Position arylation derivative of coumarin, preparation method and application thereof | 上海大学 | 2024-07-02 | — | — | CN | disclosed |