SCHEMBL5590828

SCHEMBL5590828

CCN(CC)c1ccc2c(C)c(-c3ccccc3)c(=O)oc2c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.78
KDM4E B2RXH2 9/20 0.78
MAPT P10636 7/20 0.78
L3MBTL1 Q9Y468 5/20 0.78
HPGD P15428 5/20 0.78
HIF1A Q16665 2/20 0.78
SMN1; SMN2 Q16637 2/20 0.78
EP300 Q09472 1/20 0.70
HTT P42858 6/20 0.64
TDP1 Q9NUW8 4/20 0.64
ERAP1 Q9NZ08 1/20 0.62
ATM Q13315 6/20 0.62
GLA P06280 6/20 0.62
GAA P10253 2/20 0.62
KLK7 P49862 1/20 0.62
KMT2A Q03164 7/20 0.55
MEN1 O00255 6/20 0.55
CASP1 P29466 5/20 0.55
CASP7 P55210 5/20 0.55
HSD17B10 Q99714 5/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13869309 0.92 ALDH1A1 (0.86) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL13869289 0.91 ALDH1A1 (0.72) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL13869376 0.88 ALDH1A1 (0.68) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL8132354 0.88 ALDH1A1 (1.00) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL808511 0.87 ALDH1A1 (0.73) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL28721602 0.86 ALDH1A1 (0.77) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL29569907 0.86 ALDH1A1 (0.77) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL28720726 0.85 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL30914646 0.85 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTL3MBTL1HPGD
SCHEMBL29249851 0.85 ALDH1A1 (0.75) ALDH1A1KDM4EMAPTL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512667-A Trifunctional intermediates for preparing 3'-tailed oligonucleotides DRUG ROYALTY LP1 (CA) 1996-04-30 US claimed
EP-0026088-B1 PHOTORESIST COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-11-23 EP claimed
US-4349619-A CONTAINING ANTIHALATION AGENTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US claimed
EP-0026088-A2 Photoresist compositions JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-01 EP claimed
CN-114502601-B Combination of photoinitiators and use thereof 意大利艾坚蒙树脂有限公司 2024-09-13 CN disclosed
CN-114502601-A Combination of photoinitiators and uses thereof 意大利艾坚蒙树脂有限公司 2022-05-13 CN disclosed
EP-3215339-B1 PROCESS USING PHOTOCURABLE COMPOSITIONS LAMBERTI SPA (IT) 2021-08-11 EP disclosed
CN-107073759-B Photocurable composition 蓝宝迪有限公司 2019-12-20 CN disclosed
US-10471633-B2 Photocurable compositions Lamerti SPA (IT) 2019-11-12 US disclosed
US-20170334098-A1 PHOTOCURABLE COMPOSITIONS LAMBERTI SPA (IT) 2017-11-23 US disclosed
EP-3215339-A1 PHOTOCURABLE COMPOSITIONS Lamberti SPA (IT) 2017-09-13 EP disclosed
WO-2016071304-A1 PHOTOCURABLE COMPOSITIONS LAMBERTI SPA (IT) 2016-05-12 WO disclosed
US-5419966-A Solid support for synthesis of 3'-tailed oligonucleotides MICROPROBE CORPORATION (US) 1995-05-30 US disclosed
EP-0547142-A4 MICROPROBE CORP (US) 1995-01-18 EP disclosed
EP-0547142-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE EPOCH PHARMACEUTICALS, INC. (US) 1993-06-23 EP disclosed
WO-1992003464-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE MICROPROBE CORPORATION (US) 1992-03-05 WO disclosed
US-4992351-A Recording medium having a specified photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1991-02-12 US disclosed
EP-0026088-B1 PHOTORESIST COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-11-23 EP disclosed
US-4349619-A CONTAINING ANTIHALATION AGENTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US disclosed
EP-0026088-A2 Photoresist compositions JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-01 EP disclosed