Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25808263 | 0.89 | HCAR2 (0.44) | HCAR2ATMZDHHC7MAPTCA2 | |
| SCHEMBL30914719 | 0.87 | HCAR2 (0.45) | HCAR2ATMZDHHC7MAPT | |
| SCHEMBL18723218 | 0.87 | HCAR2 (0.45) | HCAR2ATMZDHHC7MAPT | |
| SCHEMBL21694608 | 0.87 | HCAR2 (0.45) | HCAR2ATMZDHHC7MAPT | |
| SCHEMBL22627138 | 0.85 | HCAR2 (0.46) | HCAR2ATMZDHHC7MAPTCA2 | |
| SCHEMBL22465645 | 0.85 | HCAR2 (0.46) | HCAR2ATMZDHHC7MAPTCA2 | |
| SCHEMBL7870031 | 0.84 | ACHE (0.56) | ACHEBACE1MAPTPPARGGPR132 | |
| SCHEMBL7870030 | 0.84 | ACHE (0.56) | ACHEBACE1MAPTPPARGGPR132 | |
| SCHEMBL16656923 | 0.78 | ACHE (0.37) | ACHEBACE1HCAR2ATMZDHHC7 | |
| SCHEMBL16657272 | 0.78 | ACHE (0.37) | ACHEBACE1HCAR2ATMZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102730-A1 | LIPIDS AND NANOPARTICLE COMPOSITIONS FOR DELIVERING POLYNUCLEOTIDES | ORNA THERAPEUTICS, INC. (US) | 2024-05-16 | — | — | WO | disclosed |