Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30914719 | 1.00 | HCAR2 (0.45) | HCAR2ATMZDHHC7MAPTGPR84 | |
| SCHEMBL21694608 | 1.00 | HCAR2 (0.45) | HCAR2ATMZDHHC7MAPTGPR84 | |
| SCHEMBL25808263 | 0.98 | HCAR2 (0.44) | HCAR2ATMZDHHC7MAPTGPR84 | |
| SCHEMBL22627138 | 0.98 | HCAR2 (0.46) | HCAR2ATMZDHHC7MAPTGPR84 | |
| SCHEMBL22465645 | 0.98 | HCAR2 (0.46) | HCAR2ATMZDHHC7MAPTGPR84 | |
| SCHEMBL30914726 | 0.87 | ACHE (0.43) | HCAR2ATMZDHHC7MAPT | |
| SCHEMBL6476706 | 0.86 | TSHR (0.46) | HCAR2ATMMAPTALDH1A1 | |
| SCHEMBL6476703 | 0.86 | TSHR (0.46) | HCAR2ATMMAPTALDH1A1 | |
| SCHEMBL29001105 | 0.85 | TRPA1 (0.50) | HCAR2ATMMAPTGPR84FFAR1 | |
| SCHEMBL22005512 | 0.84 | ZDHHC7 (0.47) | HCAR2ZDHHC7MAPTGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9616099-B2 | Cyclosporin analogues for preventing or treating hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2017-04-11 | — | — | US | disclosed |