Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | USP9X | Q93008 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834249 | 1.00 | KDM4E (0.39) | KDM4ESMN1; SMN2ALDH1A1HRH3CXCR1 | |
| SCHEMBL21834270 | 0.89 | GRIN2B (0.38) | GRIN1GRIN2B | |
| SCHEMBL30916787 | 0.89 | GRIN2B (0.38) | GRIN1GRIN2B | |
| SCHEMBL21834279 | 0.85 | MAOB (0.41) | GRIN1GRIN2BMAOA | |
| SCHEMBL21834277 | 0.85 | MAOB (0.41) | GRIN1GRIN2BMAOA | |
| SCHEMBL21834275 | 0.85 | MAOB (0.41) | GRIN1GRIN2BMAOA | |
| SCHEMBL21834241 | 0.84 | KDM4E (0.36) | KDM4ESMN1; SMN2ALDH1A1HRH3CXCR1 | |
| SCHEMBL21834280 | 0.82 | CYP17A1 (0.39) | ALDH1A1GRIN1GRIN2B | |
| SCHEMBL23243886 | 0.81 | HRH3 (0.48) | KDM4EHRH3TLR7 | |
| SCHEMBL30916839 | 0.81 | HRH3 (0.48) | KDM4EHRH3TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272285-B | Oxadiazole-containing compound and pharmaceutical composition containing same | 爱思开生物制药株式会社 | 2024-06-07 | — | — | CN | claimed |
| CN-113272285-B | Oxadiazole-containing compound and pharmaceutical composition containing same | 爱思开生物制药株式会社 | 2024-06-07 | — | — | CN | disclosed |