SCHEMBL21834249

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30916835	1.00	KDM4E (0.39)	KDM4ESMN1; SMN2ALDH1A1HRH3CXCR1
	SCHEMBL21834270	0.89	GRIN2B (0.38)	GRIN1GRIN2B
	SCHEMBL30916787	0.89	GRIN2B (0.38)	GRIN1GRIN2B
	SCHEMBL21834279	0.85	MAOB (0.41)	GRIN1GRIN2BMAOA
	SCHEMBL21834277	0.85	MAOB (0.41)	GRIN1GRIN2BMAOA
	SCHEMBL21834275	0.85	MAOB (0.41)	GRIN1GRIN2BMAOA
	SCHEMBL21834241	0.84	KDM4E (0.36)	KDM4ESMN1; SMN2ALDH1A1HRH3CXCR1
	SCHEMBL21834280	0.82	CYP17A1 (0.39)	ALDH1A1GRIN1GRIN2B
	SCHEMBL23243886	0.81	HRH3 (0.48)	KDM4EHRH3TLR7
	SCHEMBL30916839	0.81	HRH3 (0.48)	KDM4EHRH3TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.