SCHEMBL21834277

SCHEMBL21834277

Cc1nnc(CC(O)c2cc(OCCCC(F)(F)F)ccc2F)o1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 3/20 0.41
▸ PDE2A O00408 2/20 0.38
▸ MAOA P21397 1/20 0.36
▸ GRIN2B Q13224 5/20 0.36
▸ GRIN1 Q05586 4/20 0.36
▸ CYP2C9 P11712 1/20 0.33
▸ MOGAT2 Q3SYC2 1/20 0.33
▸ MGAT2 Q10469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21834279 1.00 MAOB (0.41) MAOBPDE2AMAOAGRIN2BGRIN1
SCHEMBL21834275 1.00 MAOB (0.41) MAOBPDE2AMAOAGRIN2BGRIN1
SCHEMBL21834270 0.89 GRIN2B (0.38) PDE2AGRIN2BGRIN1CYP2C9
SCHEMBL30916787 0.89 GRIN2B (0.38) PDE2AGRIN2BGRIN1CYP2C9
SCHEMBL21834315 0.89 MAOB (0.40) MAOBPDE2AMAOAGRIN2BGRIN1
SCHEMBL21834280 0.88 CYP17A1 (0.39) GRIN2BGRIN1CYP2C9
SCHEMBL21834249 0.85 KDM4E (0.39) MAOAGRIN2BGRIN1
SCHEMBL30916835 0.85 KDM4E (0.39) MAOAGRIN2BGRIN1
SCHEMBL21834361 0.84 GPR88 (0.39) MAOBPDE2AMAOAGRIN2BGRIN1
SCHEMBL21834324 0.83 GRIN2B (0.33) GRIN2BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-01-30 — — US claimed
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2024-11-19 — — US claimed
CN-113272285-B Oxadiazole-containing compound and pharmaceutical composition containing same 爱思开生物制药株式会社 2024-06-07 — — CN claimed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US claimed
US-11603358-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-03-14 — — US claimed
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. 2022-01-27 — — US claimed
CN-113272285-A Oxadiazole-containing compound and pharmaceutical composition containing the same 爱思开生物制药株式会社 2021-08-17 — — CN claimed
EP-3854788-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME SK Biopharmaceuticals Co., Ltd. (KR) 2021-07-28 — — EP claimed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US claimed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US claimed
WO-2020060299-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 에스케이바이오팜 주식회사 2020-03-26 — — WO claimed
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-01-30 — — US disclosed
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2024-11-19 — — US disclosed
CN-113272285-B Oxadiazole-containing compound and pharmaceutical composition containing same 爱思开生物制药株式会社 2024-06-07 — — CN disclosed
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-05-18 — — US disclosed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US disclosed
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-07-06 — — US disclosed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US disclosed
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-04-22 — — US disclosed
WO-2020060299-A1 COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 에스케이바이오팜 주식회사 2020-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150955-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 MAOB 407/4885PDE2A 672/4885MAOA 690/4885
US-20220024886-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 MAOB 407/4885PDE2A 672/4885MAOA 690/4885
US-20250034101-A1 COMPOUND HAVING OXADIAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME OTC, OXA1L, ATP6V1B2 MAOB 407/4885PDE2A 672/4885MAOA 690/4885
US-11053208-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 MAOB 407/4885PDE2A 672/4885MAOA 690/4885
US-20210115001-A1 Compound Having Oxadiazole And Pharmaceutical Composition Containing The Same OTC, OXA1L, ATP6V1B2 MAOB 407/4885PDE2A 672/4885MAOA 690/4885
US-11603358-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 MAOB 407/4885PDE2A 672/4885MAOA 690/4885
US-12145914-B2 Compound having oxadiazole and pharmaceutical composition containing the same OTC, OXA1L, ATP6V1B2 MAOB 407/4885PDE2A 672/4885MAOA 690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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