Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091716 | 0.88 | FOLH1 (0.32) | LMNA | |
| SCHEMBL3108202 | 0.81 | FDPS (0.44) | LMNAADRB3FDPSPDE4DPDE3A | |
| SCHEMBL3108182 | 0.81 | FDPS (0.44) | LMNAADRB3FDPSPDE4DPDE3A | |
| SCHEMBL3105976 | 0.79 | FDPS (0.46) | LMNAADRB3FDPSPDE4DPDE3A | |
| SCHEMBL3105994 | 0.79 | FDPS (0.46) | LMNAADRB3FDPSPDE4DPDE3A | |
| SCHEMBL3103122 | 0.76 | CA12 (0.31) | — | |
| SCHEMBL3103107 | 0.76 | CA12 (0.31) | — | |
| SCHEMBL3103571 | 0.73 | ALOX15 (0.32) | — | |
| SCHEMBL2990340 | 0.73 | FOLH1 (0.33) | LMNA | |
| SCHEMBL3103653 | 0.72 | ALOX15 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |