Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 5/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | AGL | P35573 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL3390130 | 1.00 | SLC1A2 (0.48) | SLC1A2MEN1BLMKMT2AARG1 | |
| SCHEMBL114870 | 0.88 | — | — | |
| SCHEMBL7412 | 0.88 | — | — | |
| SCHEMBL178592 | 0.88 | — | — | |
| SCHEMBL2025245 | 0.88 | — | — | |
| SCHEMBL63812 | 0.88 | — | — | |
| SCHEMBL1364961 | 0.88 | — | — | |
| SCHEMBL8088 | 0.88 | — | — | |
| SCHEMBL200242 | 0.88 | — | — | |
| SCHEMBL1256601 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024023715-A1 | TOPICAL COMPOSITIONS AND USES THEREOF | Truetiva Inc. (US) | 2024-02-01 | — | — | WO | disclosed |
| US-20150110755-A1 | ELASTIN PRODUCING FIBROBLAST FORMULATIONS AND METHODS OF USING THE SAME | NULASTIN, INC. | 2015-04-23 | — | — | US | disclosed |
| US-7803522-B2 | Elastin producing fibroblast formulations and methods of using the same | HUMAN MATRIX SCIENCES, LLC (US) | 2010-09-28 | — | — | US | disclosed |
| US-20080050346-A1 | Elastin producing fibroblast formulations and methods of using the same | NULASTIN, INC. | 2008-02-28 | — | — | US | disclosed |