Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 4/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075788 | 0.92 | FOLH1 (0.58) | FOLH1SIRT5GNPATSMN1; SMN2NOD1 | |
| SCHEMBL29394341 | 0.92 | FOLH1 (0.58) | FOLH1SIRT5GNPATSMN1; SMN2NOD1 | |
| SCHEMBL2107432 | 0.86 | FOLH1 (0.46) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL1711082 | 0.86 | FOLH1 (0.46) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL27736911 | 0.86 | FOLH1 (0.46) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL1711325 | 0.85 | CPB2 (0.47) | FOLH1NPY4RNPY1RNPY2R | |
| SCHEMBL1711321 | 0.85 | CPB2 (0.47) | FOLH1NPY4RNPY1RNPY2R | |
| SCHEMBL1711732 | 0.85 | CPB2 (0.47) | FOLH1NPY4RNPY1RNPY2R | |
| SCHEMBL1711738 | 0.85 | CPB2 (0.47) | FOLH1NPY4RNPY1RNPY2R | |
| SCHEMBL31099441 | 0.85 | FOLH1 (0.56) | FOLH1SIRT5ALDH1A1CAPN1GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612124-A1 | AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY | The Johns Hopkins University (US) | 2025-09-10 | — | — | EP | claimed |
| WO-2024097320-A1 | AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-05-10 | — | — | WO | claimed |
| EP-4612124-A1 | AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY | The Johns Hopkins University (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097320-A1 | AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-05-10 | — | — | WO | disclosed |