SCHEMBL1711738

SCHEMBL1711738

CC(C)C[C@H](NC(=O)[C@H](N)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CPB2 Q96IY4 7/20 0.47
▸ FOLH1 Q04609 5/20 0.47
▸ ERAP2 Q6P179 1/20 0.47
▸ ERAP1 Q9NZ08 1/20 0.47
▸ LNPEP Q9UIQ6 1/20 0.47
▸ OPRK1 P41145 4/20 0.44
▸ OPRM1 P35372 2/20 0.44
▸ NPY1R P25929 1/20 0.41
▸ NPY2R P49146 1/20 0.41
▸ NPY4R P50391 1/20 0.41
▸ FURIN P09958 1/20 0.41
▸ PCSK6 P29122 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711732 1.00 CPB2 (0.47) CPB2FOLH1ERAP2ERAP1LNPEP
SCHEMBL1711325 1.00 CPB2 (0.47) CPB2FOLH1ERAP2ERAP1LNPEP
SCHEMBL1711321 1.00 CPB2 (0.47) CPB2FOLH1ERAP2ERAP1LNPEP
Hydrochloric Acid SCHEMBL11366046 0.99 CPB2 (0.47) CPB2FOLH1ERAP2ERAP1LNPEP
SCHEMBL31257001 0.95 CPB2 (0.45) CPB2FOLH1ERAP2ERAP1LNPEP
SCHEMBL30284335 0.95 CPB2 (0.45) CPB2FOLH1ERAP2ERAP1LNPEP
SCHEMBL30973961 0.93 FOLH1 (0.56) CPB2FOLH1ERAP2ERAP1LNPEP
SCHEMBL29782763 0.92 FOLH1 (0.51) CPB2FOLH1ERAP2ERAP1LNPEP
SCHEMBL1711315 0.92 FOLH1 (0.54) CPB2FOLH1ERAP2ERAP1LNPEP
SCHEMBL1711313 0.92 FOLH1 (0.54) CPB2FOLH1ERAP2ERAP1LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574249-A Anti-CD 45 antibodies and conjugates thereof VOR生物制药股份有限公司 2026-02-27 — — CN claimed
WO-2026041129-A1 LIGAND-CYTOTOXICITY DRUG CONJUGATES AND PHARMACEUTICAL USES THEREOF HANSOH BIO LLC (US) 2026-02-26 — — WO claimed
EP-4684807-A1 LINKER AND USE THEREOF IN LIGAND DRUG CONJUGATE Duality Biologics (Shanghai) Co., Ltd. (CN) 2026-01-28 — — EP claimed
US-12534722-B2 Euglobulin-based method for determining the biological activity of defibrotide GENTIUM S.R.L. (IT) 2026-01-27 — — US claimed
US-20260014270-A1 ANTI-CEACAM5 ANTIBODY-DRUG CONJUGATE AND METHOD FOR PREPARATION AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2026-01-15 — — US claimed
EP-4667495-A2 BIOACTIVE MOLECULE CONJUGATE, PREPARATION METHOD AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-12-24 — — EP claimed
US-20250346606-A1 CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-11-13 — — US claimed
US-20250281631-A1 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-09-11 — — US claimed
EP-4612124-A1 AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY The Johns Hopkins University (US) 2025-09-10 — — EP claimed
EP-4601701-A1 ANTIBODY-DRUG CONJUGATE BINDING TO HUMAN PTK7 AND METHOD FOR PREPARATION AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-08-20 — — EP claimed
US-11236328-B2 Euglobulin-based method for determining the biological activity of defibrotide GENTIUM S.R.L. (IT) 2022-02-01 — — US claimed
US-7705045-B2 compounds comprising a specifier linked to two or more of the same or different leaving groups via a self-eliminating multiple release spacer or spacer system, which compounds upon a single activation step, in particular removal or transformation of the specifier, release two or more leaving groups SYNTARGA, B.V. (NL) 2010-04-27 — — US claimed
EP-1370298-B1 ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS SYNTARGA BV (NL) 2008-10-08 — — EP claimed
US-7223837-B2 Anticancer prodrugs, enhance enzymatic activation rates SYNTARGA B.V. (NL) 2007-05-29 — — US claimed
US-20060116422-A1 Prodrugs built as multiple self-elimination-release spacers SYNTARGA B.V. (NL) 2006-06-01 — — US claimed
EP-1560599-A1 PRODRUGS BUILT AS MULTIPLE SELF-ELIMINATION-RELEASE SPACERS Syntarga B.V. (NL) 2005-08-10 — — EP claimed
US-20040121940-A1 Elongated and multiple spacers in activatible produgs BYONDIS B.V. (NL) 2004-06-24 — — US claimed
WO-2004043493-A1 PRODRUGS BUILT AS MULTIPLE SELF-ELIMINATION-RELEASE SPACERS SYNTARGA B.V. (NL) 2004-05-27 — — WO claimed
EP-1370298-A1 ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS Syntarga B.V. (NL) 2003-12-17 — — EP claimed
WO-2002083180-A1 ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS SYNTARGA B.V. (NL) 2002-10-24 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346606-A1 CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF WEE1, WEE2, PCLAF CPB2 2488/4885FOLH1 469/4885ERAP2 3014/4885
US-20060116422-A1 Prodrugs built as multiple self-elimination-release spacers DNPEP, GUSB, APEH CPB2 75/4885FOLH1 10/4885ERAP2 106/4885
US-20040121940-A1 Elongated and multiple spacers in activatible produgs PLG, KLK1, PKM CPB2 602/4885FOLH1 77/4885ERAP2 1536/4885
US-20260014270-A1 ANTI-CEACAM5 ANTIBODY-DRUG CONJUGATE AND METHOD FOR PREPARATION AND USE THEREOF TOP1, TNFSF10, CD2 CPB2 3915/4885FOLH1 387/4885ERAP2 4371/4885
US-12534722-B2 Euglobulin-based method for determining the biological activity of defibrotide FGB, PLG, F2 CPB2 244/4885FOLH1 1337/4885ERAP2 1936/4885
US-20250281631-A1 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF TOP1, TOP2A, TOP2B CPB2 3524/4885FOLH1 132/4885ERAP2 3204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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