SCHEMBL30919306

SCHEMBL30919306

C=CCOC(=O)[C@@H](N)CCC(=O)N[C@@H](CCC(=O)C=[N+]=[N-])C(=O)N[C@@H](CCC(=O)C=[N+]=[N-])C(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 4/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LTA4H P09960 1/20 0.31
GLO1 Q04760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30919314 0.96 SMN1; SMN2 (0.35) NOD1SMN1; SMN2LTA4HGLO1
SCHEMBL30919281 0.91 LTA4H (0.36) NOD1LTA4HGLO1
SCHEMBL30919275 0.89 NOD1 (0.44) NOD1SMN1; SMN2GLO1
SCHEMBL30919307 0.89 NOD1 (0.44) NOD1SMN1; SMN2GLO1
SCHEMBL30919273 0.87 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL30919271 0.87 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL30919295 0.83 KMT2A (0.32)
SCHEMBL30919265 0.83 DPP4 (0.32) LTA4H
SCHEMBL30919294 0.81 POLB (0.30)
SCHEMBL30919269 0.80 NOD1 (0.35) NOD1GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4612124-A1 AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY The Johns Hopkins University (US) 2025-09-10 EP disclosed
WO-2024097320-A1 AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY THE JOHNS HOPKINS UNIVERSITY (US) 2024-05-10 WO disclosed