Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.36 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.36 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.35 |
| ▸ | BCR | P11274 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27265524 | 0.99 | MAPK13 (0.40) | MAPK13MAPK12MAPK11MAPK14AR | |
| SCHEMBL30919727 | 0.94 | SMN1; SMN2 (0.36) | MAPK13MAPK12MAPK11MAPK14AR | |
| SCHEMBL30919604 | 0.91 | SMN1; SMN2 (0.36) | MAPK13MAPK12MAPK11MAPK14HCRTR2 | |
| SCHEMBL30919913 | 0.91 | SMN1; SMN2 (0.36) | MAPK13MAPK12MAPK11MAPK14HCRTR2 | |
| SCHEMBL27265149 | 0.78 | HRH3 (0.41) | HCRTR2 | |
| SCHEMBL30919945 | 0.77 | NPC1 (0.46) | HCRTR2SMN1; SMN2MAPT | |
| SCHEMBL30919792 | 0.77 | CCNE2 (0.41) | MAPK13MAPK12MAPK11MAPK14HCRTR2 | |
| SCHEMBL30919906 | 0.77 | CCNE2 (0.41) | MAPK13MAPK12MAPK11MAPK14HCRTR2 | |
| SCHEMBL30919856 | 0.77 | CCNE2 (0.41) | MAPK13MAPK12MAPK11MAPK14HCRTR2 | |
| SCHEMBL1935226 | 0.76 | SMN1; SMN2 (0.49) | HCRTR2SMN1; SMN2RPS6KA5RPS6KA4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |