Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30919910 | 0.99 | CDK1 (0.47) | CDK1CCNB1CCNE1CDK2JAK2 | |
| SCHEMBL30919647 | 0.97 | CDK1 (0.47) | CDK1CCNB1CCNE1CDK2JAK2 | |
| SCHEMBL31333791 | 0.94 | CDK1 (0.47) | CDK1CCNB1CCNE1CDK2JAK2 | |
| SCHEMBL30919561 | 0.88 | CHRNB2 (0.47) | JAK2JAK1TYK2JAK3AXL | |
| SCHEMBL22900850 | 0.88 | CCNE1 (0.58) | CDK1CCNB1CCNE1CDK2JAK2 | |
| SCHEMBL30926322 | 0.87 | CDK1 (0.47) | CDK1CCNB1CCNE1CDK2CCNB2 | |
| SCHEMBL17059335 | 0.82 | KDM5B (0.48) | CDK1CCNB1CCNE1CDK2JAK2 | |
| SCHEMBL30919558 | 0.81 | CDK1 (0.44) | CDK1CCNB1CCNE1CDK2JAK2 | |
| SCHEMBL17059346 | 0.77 | EGFR (0.53) | CDK1CCNB1CCNE1CDK2JAK2 | |
| SCHEMBL17059188 | 0.75 | CCNB2 (0.51) | CDK1CCNB1CCNE1CDK2KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |