Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | TYK2 | P29597 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30919511 | 0.87 | FGFR3 (0.45) | CDK1CDK2CCNB1CCNE1CDK8 | |
| SCHEMBL30919757 | 0.81 | CDK1 (0.47) | CDK1CDK2CCNB1CCNE1BMPR1A | |
| SCHEMBL30919647 | 0.81 | CDK1 (0.47) | CDK1CDK2CCNB1CCNE1BMPR1A | |
| SCHEMBL30919910 | 0.80 | CDK1 (0.47) | CDK1CDK2CCNB1CCNE1BMPR1A | |
| SCHEMBL31333791 | 0.79 | CDK1 (0.47) | CDK1CDK2CCNB1CCNE1ACVR1 | |
| SCHEMBL30926322 | 0.77 | CDK1 (0.47) | CDK1CDK2CCNB1CCNE1BMPR1A | |
| SCHEMBL17059346 | 0.76 | EGFR (0.53) | CDK1CDK2CCNB1CCNE1CDK8 | |
| SCHEMBL31333688 | 0.74 | CDK2 (0.64) | CDK1CDK2CCNB1CCNE1IGF1R | |
| SCHEMBL22900850 | 0.73 | CCNE1 (0.58) | CDK1CDK2CCNB1CCNE1JAK1 | |
| SCHEMBL30919561 | 0.73 | CHRNB2 (0.47) | JAK1TYK2JAK3JAK2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |