Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27265870 | 1.00 | DDB1 (0.53) | DDB1CRBNPSEN1PSEN2APH1B | |
| SCHEMBL30938959 | 0.96 | DDB1 (0.55) | DDB1CRBNPSEN1PSEN2APH1B | |
| SCHEMBL27265872 | 0.88 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL30919905 | 0.88 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL31601585 | 0.86 | CRBN (0.52) | DDB1CRBN | |
| SCHEMBL19586978 | 0.84 | DDB1 (0.44) | DDB1CRBNPSEN1PSEN2APH1B | |
| SCHEMBL29971694 | 0.84 | DDB1 (0.44) | DDB1CRBNPSEN1PSEN2APH1B | |
| SCHEMBL30938883 | 0.84 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL31553731 | 0.82 | DDB1 (0.54) | DDB1CRBNPIK3CAMTORPRKDC | |
| SCHEMBL27178269 | 0.82 | CRBN (0.47) | DDB1CRBNPIK3CAPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |