SCHEMBL31601585

SCHEMBL31601585

Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(OCCCCCCC(=O)OC(C)(C)C)cc21

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 17/20 0.52
▸ DDB1 Q16531 16/20 0.52
▸ PDE3B Q13370 3/20 0.37
▸ PDE3A Q14432 3/20 0.37
▸ PDE2A O00408 1/20 0.37
▸ P2RY12 Q9H244 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30938959 0.89 DDB1 (0.55) CRBNDDB1
SCHEMBL31601448 0.88 CRBN (0.56) CRBNDDB1PDE3BPDE3APDE2A
SCHEMBL30289457 0.88 CRBN (0.58) CRBNDDB1
SCHEMBL23842395 0.88 CRBN (0.58) CRBNDDB1
SCHEMBL23832518 0.87 CRBN (0.59) CRBNDDB1
SCHEMBL23832581 0.86 CRBN (0.60) CRBNDDB1
SCHEMBL30919790 0.86 DDB1 (0.53) CRBNDDB1
SCHEMBL27265870 0.86 DDB1 (0.53) CRBNDDB1
SCHEMBL22525515 0.86 CRBN (0.51) CRBNDDB1
SCHEMBL27178269 0.85 CRBN (0.47) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108411-A1 EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京沐华生物科技有限责任公司 2025-05-30 — — WO disclosed
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