Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27265872 | 1.00 | DDB1 (0.58) | DDB1CRBNKDM4EMEN1KMT2A | |
| SCHEMBL30938883 | 0.96 | DDB1 (0.59) | DDB1CRBNKDM4EMEN1KMT2A | |
| SCHEMBL27265870 | 0.88 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL30919790 | 0.88 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL31601448 | 0.84 | CRBN (0.56) | DDB1CRBN | |
| SCHEMBL30938959 | 0.84 | DDB1 (0.55) | DDB1CRBN | |
| SCHEMBL19586625 | 0.82 | DDB1 (0.44) | DDB1CRBNKDM4EMCL1 | |
| SCHEMBL31553873 | 0.81 | CRBN (0.61) | DDB1CRBNKMT2AIKZF3 | |
| SCHEMBL24821105 | 0.81 | CRBN (0.61) | DDB1CRBNKDM4EIKZF3 | |
| SCHEMBL21760046 | 0.80 | CRBN (0.69) | DDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |