Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24664466 | 0.77 | FGFR1 (0.41) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL29608206 | 0.77 | FGFR1 (0.41) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL17059212 | 0.76 | CCNE2 (0.49) | PIM1CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL30919567 | 0.75 | ATR (0.36) | CDK2 | |
| SCHEMBL22900850 | 0.74 | CCNE1 (0.58) | LRRK2JAK2CDK1CCNB1CCNE1 | |
| SCHEMBL31333791 | 0.73 | CDK1 (0.47) | JAK2KDM5AACVR1CDK1CCNB1 | |
| SCHEMBL29528376 | 0.72 | CCNC (0.49) | JAK2 | |
| SCHEMBL24301059 | 0.72 | CCNC (0.49) | JAK2 | |
| SCHEMBL22900922 | 0.72 | CCNE1 (0.59) | LRRK2JAK2CDK1CCNB1CCNE1 | |
| SCHEMBL30919757 | 0.71 | CDK1 (0.47) | LRRK2JAK2KDM5ABMPR1AACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |