SCHEMBL30920440

SCHEMBL30920440

COc1cc2c(cc1C=O)cc(CNC(=O)C1(C)CC1)n2S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MTNR1B P49286 1/20 0.40
▸ PPARG P37231 4/20 0.37
▸ PPARD Q03181 2/20 0.37
▸ PKM P14618 5/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ RAB9A P51151 1/20 0.35
▸ PPARA Q07869 3/20 0.35
▸ L3MBTL1 Q9Y468 3/20 0.34
▸ LMNA P02545 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ MAPT P10636 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ NOD2 Q9HC29 1/20 0.34
▸ NOD1 Q9Y239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27247436 0.97 MTNR1B (0.40) MTNR1BPPARGPPARDPKMMEN1
SCHEMBL30920125 0.89 MTNR1B (0.39) MTNR1BPPARGPPARDPKMMEN1
SCHEMBL27247495 0.89 MTNR1B (0.39) MTNR1BPPARGPPARDPKMMEN1
SCHEMBL30920671 0.89 PPARG (0.38) MTNR1BPPARGPPARDKMT2ARAB9A
SCHEMBL27247611 0.89 PPARG (0.38) MTNR1BPPARGPPARDKMT2ARAB9A
SCHEMBL27246722 0.88 MTNR1B (0.46) MTNR1BPPARGPPARDPKMMEN1
SCHEMBL30920651 0.88 ALDH1A1 (0.41) MTNR1BPPARGPPARDPKMMEN1
SCHEMBL30920502 0.88 MTNR1B (0.41) MTNR1BPPARGPPARDPKMMEN1
SCHEMBL27247530 0.88 ALDH1A1 (0.41) MTNR1BPPARGPPARDPKMMEN1
SCHEMBL27247431 0.88 MTNR1B (0.41) MTNR1BPPARGPPARDPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
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