SCHEMBL30920641

SCHEMBL30920641

Cc1cc(COc2cc3[nH]c(CNC(=O)N4CC[C@@H](F)C4)cc3cc2Cl)on1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.38
▸ MAPT P10636 1/20 0.38
▸ RAB9A P51151 5/20 0.37
▸ KDM1A O60341 4/20 0.37
▸ NPC1 O15118 4/20 0.36
▸ GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27247258 1.00 MEN1 (0.40) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL30920540 1.00 MEN1 (0.40) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL27247282 1.00 MEN1 (0.40) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL27247316 0.94 MAPT (0.39) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL30920647 0.94 MAPT (0.39) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL30920646 0.94 MAPT (0.39) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL30920345 0.91 KMT2A (0.40) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL27247846 0.91 KMT2A (0.40) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL30920768 0.89 NPC1 (0.43) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL30920800 0.89 NPC1 (0.41) MEN1KMT2AALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 — — US disclosed
WO-2024081748-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-04-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 MEN1 2882/4885KMT2A 3366/4885ALDH1A1 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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