Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27247094 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL27247777 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9ANPC1PKMCYP3A4 | |
| SCHEMBL30920782 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL27246773 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL27246962 | 0.84 | RAB9A (0.41) | SMN1; SMN2MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL30920360 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2MTNR1AMTNR1BRAB9AMEN1 | |
| SCHEMBL30920207 | 0.84 | RAB9A (0.41) | SMN1; SMN2MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL30920655 | 0.84 | MTNR1A (0.41) | SMN1; SMN2MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL27247432 | 0.84 | MTNR1A (0.41) | SMN1; SMN2MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL27247882 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2MTNR1AMTNR1BRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4601635-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |