Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 4/20 | 0.34 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30920347 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2IDH1GRM5FLT1EPHA2 | |
| SCHEMBL30920710 | 0.90 | CACNA1H (0.38) | SMN1; SMN2CACNA1HCACNA1BCACNA1CBCHE | |
| SCHEMBL30946269 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2CACNA1BIDH1GRM5FLT1 | |
| SCHEMBL30920151 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2IDH1FLT1EPHA2KDR | |
| SCHEMBL30946073 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2IDH1GRM5FLT1EPHA2 | |
| SCHEMBL27247829 | 0.88 | CACNA1B (0.44) | SMN1; SMN2CACNA1HCACNA1BCACNA1CMRGPRX4 | |
| SCHEMBL30946099 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2IDH1GRM5FLT1EPHA2 | |
| SCHEMBL30920124 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2IDH1FLT1EPHA2KDR | |
| SCHEMBL30920564 | 0.87 | CACNA1H (0.37) | SMN1; SMN2CACNA1HCACNA1BCACNA1CBCHE | |
| SCHEMBL27247540 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2IDH1GRM5FLT1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4601635-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | HERCULES CAPITAL, INC., AS AGENT | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | SLC6A19, SLC2A9, SLC6A3 | SMN1; SMN2 375/4885CACNA1H 1340/4885CACNA1B 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.