Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148741 | 0.79 | KMT2A (0.38) | ACLY | |
| SCHEMBL4148744 | 0.79 | KMT2A (0.38) | ACLY | |
| SCHEMBL4830100 | 0.64 | KDM4E (0.37) | SRPK1RPS6KB2MAPKAPK2CSNK2A1RPS6KA3 | |
| SCHEMBL4826413 | 0.63 | MAPK8 (0.34) | MAPKAPK2RPS6KA3 | |
| SCHEMBL4825624 | 0.61 | CA12 (0.35) | SRPK1RPS6KB2RPS6KA3ACLY | |
| SCHEMBL3244153 | 0.60 | SRD5A2 (0.43) | AKR1C3ACLY | |
| SCHEMBL4830030 | 0.60 | SLC22A12 (0.35) | MAPKAPK2CSNK2A2CSNK2BCSNK2A1RPS6KA3 | |
| SCHEMBL4139797 | 0.60 | KMT2A (0.37) | ACLY | |
| SCHEMBL3236134 | 0.58 | KMT2A (0.38) | ACLY | |
| SCHEMBL17515229 | 0.58 | TDP1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795247-B2 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | disclosed |
| US-20060100262-A1 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICHERCHEDI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IRMB) (IT) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100262-A1 | Tetracyclic indole derivatives as antiviral agents | IDO1, ZC3HAV1, IDO2 | SRPK1 2862/4885RPS6KB2 3519/4885AKR1C3 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.