SCHEMBL30920751

SCHEMBL30920751

CC(C)(C)OC(=O)NCc1cc2cc(OC(F)(F)F)c(CCc3cocn3)cc2[nH]1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CACNA1H O95180 1/20 0.37
▸ CACNA1B Q00975 1/20 0.37
▸ CACNA1C Q13936 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27247185 0.89 FFAR1 (0.32) SMN1; SMN2
SCHEMBL30920326 0.87 CACNA1H (0.37) CACNA1HCACNA1BCACNA1CSMN1; SMN2CYP1A2
SCHEMBL27247723 0.85 IKBKB (0.31) —
SCHEMBL27247511 0.83 EPHX2 (0.37) —
SCHEMBL27247138 0.83 EPHX2 (0.37) —
Hydrochloric Acid SCHEMBL27247030 0.79 HRH4 (0.35) —
SCHEMBL27247742 0.75 KLKB1 (0.31) SMN1; SMN2
SCHEMBL30920547 0.75 CACNA1H (0.37) CACNA1HCACNA1BCACNA1CSMN1; SMN2CYP1A2
SCHEMBL30920769 0.74 PPARG (0.35) —
SCHEMBL30920564 0.73 CACNA1H (0.37) CACNA1HCACNA1BCACNA1CSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 CACNA1H 1340/4885CACNA1B 559/4885CACNA1C 1103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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