Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PPIB | P23284 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLQ | O75417 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3158672 | 0.97 | DRD4 (0.49) | DRD4HRH3LMNARAD52OPRK1 | |
| SCHEMBL3148838 | 0.95 | DRD4 (0.48) | DRD4HRH3LMNARAD52OPRK1 | |
| SCHEMBL4490990 | 0.92 | DRD4 (0.46) | DRD4HRH3LMNASIGMAR1MAPK1 | |
| SCHEMBL4487965 | 0.88 | DRD4 (0.50) | DRD4HRH3LMNARAD52PPIB | |
| SCHEMBL436539 | 0.88 | DRD4 (0.50) | DRD4HRH3LMNAGFERALDH1A1 | |
| SCHEMBL24538671 | 0.87 | DRD4 (0.49) | DRD4HRH3LMNAOPRK1PPIB | |
| SCHEMBL18851564 | 0.87 | DRD4 (0.46) | DRD4HRH3LMNAPPIBSIGMAR1 | |
| SCHEMBL3144650 | 0.87 | HRH3 (0.58) | DRD4HRH3LMNAALDH1A1TP53 | |
| SCHEMBL17976084 | 0.85 | DRD4 (0.48) | DRD4HRH3LMNAPPIBALDH1A1 | |
| SCHEMBL8354585 | 0.83 | LMNA (0.61) | DRD4HRH3LMNASIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612149-A1 | PYRIDO[2,3-D]PYRIMIDIN-2-AMINE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |