Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12088076 | 0.92 | MEN1 (0.48) | MEN1KMT2APPARAKDM4EMAPT | |
| SCHEMBL14160646 | 0.91 | MEN1 (0.46) | MEN1KMT2APPARAKDM4EMAPT | |
| SCHEMBL10091833 | 0.89 | MEN1 (0.44) | MEN1KMT2APPARAKDM4EMAPT | |
| SCHEMBL23685784 | 0.88 | PPARA (0.45) | MEN1KMT2APPARAKDM4EMAPT | |
| SCHEMBL7050086 | 0.88 | MEN1 (0.44) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL15413120 | 0.87 | KMT2A (0.48) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL10091841 | 0.87 | PPARA (0.46) | MEN1KMT2APPARAKDM4EMAPT | |
| SCHEMBL12088158 | 0.86 | MEN1 (0.41) | MEN1KMT2APPARAKDM4EMAPT | |
| SCHEMBL10091826 | 0.85 | PPARA (0.42) | MEN1KMT2APPARAKDM4EMAPT | |
| SCHEMBL10091840 | 0.85 | PPARA (0.42) | MEN1KMT2APPARAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872489-B1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2016-12-21 | — | — | EP | disclosed |
| US-9512080-B2 | Synthesis of acridinium compounds by N-alkylation of acridans | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512080-B2 | Synthesis of acridinium compounds by N-alkylation of acridans | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-12-06 | — | — | US | disclosed |
| CN-101918367-B | Acridine compounds Facile N-alkylation in ionic liquid | 西门子医疗保健诊断公司 | 2016-08-24 | — | — | CN | disclosed |
| US-20150197491-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-20150197491-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2015-07-16 | — | — | US | disclosed |
| EP-2872489-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | Siemens Healthcare Diagnostics Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014011762-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | SIEMENS HEAL THCARE DIAGNOSTICS INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| EP-2215063-B1 | FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2013-10-30 | — | — | EP | disclosed |
| US-8293908-B2 | Facile N-alkylation of acridine compounds in ionic liquids | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20100256380-A1 | FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-10-07 | — | — | US | disclosed |
| EP-2215063-A1 | FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS | Siemens Healthcare Diagnostics Inc. (US) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009067417-A1 | FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS | SIEMENS HEATHCARE DIAGNOSTICS INC. (US) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256380-A1 | FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS | ACR, MGMT, DNMT3A | MEN1 1088/4885KMT2A 1190/4885PPARA 2876/4885 |
| US-20150197491-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | ACR, MCL1, MGMT | MEN1 983/4885KMT2A 1929/4885PPARA 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.