Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3092289 | 0.86 | MEN1 (0.52) | MEN1KMT2APPARAMAPTL3MBTL1 | |
| SCHEMBL12088076 | 0.83 | MEN1 (0.48) | MEN1KMT2APPARAMAPTL3MBTL1 | |
| SCHEMBL12088068 | 0.82 | HRH3 (0.41) | MEN1KMT2AHTTPLA2G2AKDM4E | |
| SCHEMBL16141110 | 0.81 | PLA2G2A (0.40) | KMT2AMAPTPLA2G2AKDM4EALDH1A1 | |
| SCHEMBL16141112 | 0.81 | PLA2G2A (0.40) | KMT2AMAPTPLA2G2AKDM4EALDH1A1 | |
| SCHEMBL14160646 | 0.80 | MEN1 (0.46) | MEN1KMT2APPARAMAPTL3MBTL1 | |
| SCHEMBL23685784 | 0.80 | PPARA (0.45) | MEN1KMT2APPARAMAPTL3MBTL1 | |
| SCHEMBL10091833 | 0.79 | MEN1 (0.44) | MEN1KMT2APPARAMAPTL3MBTL1 | |
| SCHEMBL15413120 | 0.78 | KMT2A (0.48) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL3039691 | 0.78 | KDM4E (0.47) | MEN1KMT2APPARAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9575062-B2 | Zwitterion-containing acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9575062-B2 | Zwitterion-containing acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-02-21 | — | — | US | disclosed |
| EP-3067345-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | Siemens Healthcare Diagnostics Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| EP-2501681-B1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2016-05-25 | — | — | EP | disclosed |
| US-20140295575-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-10-02 | — | — | US | disclosed |
| US-20140295575-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-10-02 | — | — | US | disclosed |
| US-8778624-B2 | Zwitterion-containing acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778624-B2 | Zwitterion-containing acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20120225497-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-20120225497-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2012-09-06 | — | — | US | disclosed |
| WO-2011060228-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225497-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | ACR, SSB, FCGR3B | MEN1 3495/4885KMT2A 4345/4885PPARA 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.