SCHEMBL30923484

SCHEMBL30923484

NC(=O)c1ccncc1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 15/20 0.62
KDM6B O15054 5/20 0.62
KDM4E B2RXH2 3/20 0.62
KDM4D Q6B0I6 3/20 0.62
TDP1 Q9NUW8 2/20 0.62
KDM4A O75164 2/20 0.62
MEN1 O00255 1/20 0.62
ALDH1A1 P00352 1/20 0.62
MAPT P10636 1/20 0.62
THRB P10828 1/20 0.62
KMT2A Q03164 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
SIRT3 Q9NTG7 2/20 0.60
ADORA3 P0DMS8 1/20 0.45
TSHR P16473 1/20 0.45
MC4R P32245 1/20 0.45
ADRA1A P35348 1/20 0.45
MC3R P41968 1/20 0.45
HTT P42858 1/20 0.45
F7 P08709 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3392091 1.00 KDM4C (0.62) KDM4CKDM6BKDM4EKDM4DTDP1
Ammonia Solution, Strong SCHEMBL11417342 0.98 KDM4C (0.60) KDM4CKDM6BKDM4EKDM4DTDP1
SCHEMBL11870062 0.92 KDM4C (0.62) KDM4CKDM6BKDM4EKDM4DTDP1
SCHEMBL1687197 0.89 TDP1 (0.67) KDM4CKDM6BKDM4EKDM4DTDP1
SCHEMBL27758655 0.89 KDM4C (0.63) KDM4CKDM6BKDM4EKDM4DTDP1
SCHEMBL1330970 0.89 TDP1 (0.67) KDM4CKDM6BKDM4EKDM4DTDP1
SCHEMBL29416303 0.87 KDM4C (0.65) KDM4CKDM6BKDM4EKDM4DTDP1
SCHEMBL71335 0.87 KDM4C (0.65) KDM4CKDM6BKDM4EKDM4DTDP1
Hydrochloric Acid SCHEMBL10697489 0.85 KDM4C (0.63) KDM4CKDM6BKDM4EKDM4DTDP1
SCHEMBL28799175 0.85 KDM4C (0.63) KDM4CKDM6BKDM4EKDM4DTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113354579-B High-yield synthesis method of methyl 4-aminonicotinate 安徽大学 2024-05-14 CN claimed
CN-113354579-B High-yield synthesis method of methyl 4-aminonicotinate 安徽大学 2024-05-14 CN disclosed