Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.62 |
| ▸ | KDM6B | O15054 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KDM4A | O75164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30923484 | 1.00 | KDM4C (0.62) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| Ammonia Solution, Strong SCHEMBL11417342 | 0.98 | KDM4C (0.60) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL11870062 | 0.92 | KDM4C (0.62) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL1687197 | 0.89 | TDP1 (0.67) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL27758655 | 0.89 | KDM4C (0.63) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL1330970 | 0.89 | TDP1 (0.67) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL29416303 | 0.87 | KDM4C (0.65) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL71335 | 0.87 | KDM4C (0.65) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| Hydrochloric Acid SCHEMBL10697489 | 0.85 | KDM4C (0.63) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL28799175 | 0.85 | KDM4C (0.63) | KDM4CKDM6BKDM4EKDM4DTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354579-B | High-yield synthesis method of methyl 4-aminonicotinate | 安徽大学 | 2024-05-14 | — | — | CN | claimed |
| CN-113354579-A | High-yield synthesis method of 4-amino methyl nicotinate | 安徽大学 | 2021-09-07 | — | — | CN | claimed |
| CN-113354579-B | High-yield synthesis method of methyl 4-aminonicotinate | 安徽大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117510404-A | Preparation method of 4-aminonicotinic acid | 山西永津集团有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-113354579-A | High-yield synthesis method of 4-amino methyl nicotinate | 安徽大学 | 2021-09-07 | — | — | CN | disclosed |
| US-11072634-B2 | Inhibitors of transglutaminases | ZEDIRA GMBH (DE) | 2021-07-27 | — | — | US | disclosed |
| WO-2020204191-A1 | COSMETIC CONTAINING ULTRAVIOLET WAVELENGTH CONVERSION SUBSTANCE AND MEDICINAL AGENT | 株式会社 資生堂 | 2020-10-08 | — | — | WO | disclosed |
| EP-3689897-A1 | A CNP CYCLIC PEPTIDE AND A MEDICAMENT, EXTERNAL PREPARATION AND COSMETIC CONTAINING THE CYCLIC PEPTIDE | Igisu Co., Ltd. (JP) | 2020-08-05 | — | — | EP | disclosed |
| CN-110483388-B | Preparation method of nicotinic acid derivative | 新发药业有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-110483388-A | A kind of preparation method of nicotinic acid derivates | XINFA PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | disclosed |
| US-20190322700-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2019-10-24 | — | — | US | disclosed |
| US-4885291-A | 1-carba(dethia)-3-cephem derivatives | ELI LILLY AND COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0324562-A1 | 1-Carba(dethia)-3-cephem derivatives | ELI LILLY AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| EP-0322616-A2 | Novel 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and nivel intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0254951-A2 | 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| EP-0059683-A2 | 7-Acylamido-3-cephem-4-carboxylic acids, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-09-08 | — | — | EP | disclosed |
| US-3947442-A | Method for producing heterocyclic acid anhydrides and pyrimidinediones | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3947416-A | Azaisatoic anhydrides | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322700-A1 | INHIBITORS OF TRANSGLUTAMINASES | TGM2, TGM3, TGM1 | KDM4C 802/4885KDM6B 439/4885KDM4E 911/4885 |
| US-11072634-B2 | Inhibitors of transglutaminases | TGM2, TGM3, TGM1 | KDM4C 802/4885KDM6B 439/4885KDM4E 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.